Opportunistic Assessment of Bone Density in the Cervical Spine Using Dental Cone Beam Computed Tomography

Researched Under: Dr. Chamith Rajapakse
University of Pennsylvania
I'm developing an opportunistic osteoporosis screening method using routine dental CBCT scans by correlating cervical vertebra density patterns with clinical bone health standards, potentially enabling earlier detection through existing dental imaging workflows.

I've been researching the use of dental Cone Beam Computed Tomography (CBCT) for opportunistic bone density assessment for the past three years at the University of Pennsylvania under Dr. Chamith Rajapakse. The study looks into whether routine dental CBCT scans - more widely available and less expensive and radiation-intensive than conventional CT, can be used to find early signs of osteoporosis.

In order to facilitate cross-anatomical validation, we also assess tooth density and femur CT scans in addition to our primary analysis of radiographic density patterns in the C3 cervical vertebra.

We extracted voxel-level intensity features from more than 1,000 patient scans, calibrated density values across imaging modalities, and compared metrics derived from CBCT with the clinical gold standard, DXA-based T-scores.

I found strong connections between CBCT intensity patterns and DXA measurements in preliminary results, suggesting that CBCT could serve as an accessible, opportunistic screening method—especially for patients who regularly undergo dental imaging but may not receive dedicated bone density evaluations.

This research has broader clinical implications: if dental CBCT scans can reliably flag low bone density, dentists and oral surgeons could play a critical role in identifying at-risk individuals earlier, enabling timely medical follow-up.

Our ongoing work focuses on refining segmentation methods, normalizing scan data for cross-machine compatibility, and developing machine-learning models to automate risk classification with greater precision.

Download My Paper (PDF)
Project preview

Early Fault Detection in Endodontic Instruments Using Signal Processing and Machine Learning

Researched Under: Dr. Chandrasekhar Nataraj
Villanova University
I developed a real-time predictive maintenance system for endodontic root canal files using accelerometer data, signal processing, and machine learning to detect tool fatigue and prevent fractures before clinical failure occurs.

For the past year, I've conducted research under Dr. Chandrasekhar Nataraj at Villanova University exploring my project, Early Fault Detection in Endodontic Instruments Using Signal Processing and Machine Learning.

I developed a real-time system that identifies early signs of stress and microfractures in dental root-canal files.

My findings revealed that monitoring irregular frequency magnitudes and unstable wavelet energy levels are reliable predictors of tool fatigue—often appearing well before a file visibly fails.

Download My Paper (PDF)

Elephancy

Presented at: University of Pennsylvania's PennApps 2024
I created an immersive VR tool that converts text prompts into explorable 3D scenes using LLMs and image generation, enabling people with aphantasia to experience visual concepts they cannot mentally visualize.
Elephancy Example

Elephancy - an immersive VR visualization tool created to help people who have aphantasia.

Our prompts expanded into a structured scene description by a language model.

Through immersive external imagery, this develops a new type of accessible technology for Aphantasia.

3D Anatomical Model from CT Scans

Self Work
I developed an automated pipeline using 3D Slicer and TotalSegmentator AI.
Project preview

3D Anatomical Model from CT Scans is a highly advanced medical imaging project.

With 3D Slicer as the primary image-processing software.

These processed models are further made compatible with AR/VR systems.

Download My Paper (PDF)

High-Degree Polynomial Root Finder

Presented at: Delaware Valley Science Fair, the Air Products Young Innovators Award, and Programming at the 2023 Regional Media and Design Competition.
Built a Java-based polynomial root solver using Newton-Raphson iteration.
Projectile Example

High Degree Polynomial Root Solver is an object of a Java-based numerical computation project.

In order to check the accuracy, comparisons with manually derived approximations.

The work earned 1st place at the Delaware Valley Science Fair.

Download My Paper (PDF)